2nd Hippo Pathway Targeted Drug Development Summit Boston Park Plaza, Boston

It has been long understood that the Hippo pathway has clear therapeutic potential in the treatment of cancer resistance, tissue repair, and cardiac regeneration. Now, this highly attractive and targetable pathway is experiencing investment, collaboration, and interest from biopharma and academia; a once unexploited pathway is now on the brink of its first positive phase 1 clinical readout.

A new frontier in precision medicine is emerging as novel data and literature forge a wider and more developed mechanistic understanding of this valuable signaling pathway. Discovery of new upstream targets to evolve the landscape of targetable nodes and therapeutic interventions, from small molecule approaches to novel modalities that target the TEAD transcription complex.

The 2nd Hippo Pathway Targeted Drug Development Summit has been established as the first and only industry-led forum, focussed on progressing the functional understanding and realizing the potential of the Hippo signaling pathway to enhance the discovery, translation and clinical development of safe and effective drugs in oncology, regenerative medicine and beyond.